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Koichi Sato Selected Research

G-Protein-Coupled Receptors (Receptors, G Protein Coupled)

1/2021Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone.
11/2020A missense mutation of Leu74Pro of OGR1 found in familial amelogenesis imperfecta actually causes the loss of the pH-sensing mechanism.
10/2020The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model.
4/2020Involvement of GPR4 in increased growth hormone and prolactin expressions by extracellular acidification in MtT/S cells.
4/2020Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin.
10/2019Characterization of molecular mechanisms of extracellular acidification-induced intracellular Ca2+ increase in LβT2 cells.
1/2019Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone.
4/2018Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species.
10/2017The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction.
8/2017Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4.
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Koichi Sato Research Topics

Disease

56Neoplasms (Cancer)
11/2021 - 01/2003
19Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 10/2004
13Stomach Neoplasms (Stomach Cancer)
10/2022 - 07/2007
13Inflammation (Inflammations)
05/2022 - 09/2003
12Hypertension (High Blood Pressure)
01/2022 - 06/2003
12Sepsis (Septicemia)
12/2020 - 06/2011
9Alzheimer Disease (Alzheimer's Disease)
02/2019 - 03/2003
8Fanconi Anemia (Fanconi's Anemia)
01/2020 - 01/2011
7Spasm (Spasms)
01/2022 - 11/2019
7Atherosclerosis
01/2022 - 06/2003
7Neoplasm Metastasis (Metastasis)
11/2021 - 07/2007
7Disseminated Intravascular Coagulation
07/2020 - 12/2015
7Hypotension (Low Blood Pressure)
12/2019 - 08/2002
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2022 - 01/2018
6Myocardial Infarction
01/2022 - 01/2015
6Colorectal Neoplasms (Colorectal Cancer)
04/2021 - 01/2016
6Thrombosis (Thrombus)
07/2020 - 06/2002
6Ascites
06/2012 - 02/2004
5Pathologic Constriction (Stenosis)
01/2022 - 02/2011
5Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2007
5Heart Failure
01/2022 - 04/2007
5Carcinoma (Carcinomatosis)
11/2021 - 01/2003
5Type 2 Diabetes Mellitus (MODY)
01/2021 - 01/2002
4Hypoxia (Hypoxemia)
01/2022 - 04/2002
4Coronary Artery Disease (Coronary Atherosclerosis)
01/2022 - 08/2020
4Dyslipidemias (Dyslipidemia)
01/2022 - 04/2008
4Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
11/2021 - 02/2012
4Fibrosis (Cirrhosis)
02/2021 - 01/2019
4Colonic Neoplasms (Colon Cancer)
10/2020 - 09/2003
4Pancreatic Neoplasms (Pancreatic Cancer)
03/2020 - 02/2004
4Hemorrhage
03/2020 - 01/2006
4Lymphoma (Lymphomas)
02/2020 - 01/2013
4Septic Shock (Toxic Shock Syndrome)
12/2015 - 03/2007
4Glioma (Gliomas)
12/2009 - 03/2003
3Shock
01/2022 - 01/2017
3Unstable Angina
01/2022 - 08/2020
3Diabetic Nephropathies (Diabetic Nephropathy)
01/2022 - 01/2021
3Myocardial Ischemia (Ischemic Heart Diseases)
08/2021 - 12/2019
3Adenocarcinoma
06/2021 - 09/2010
3Genomic Instability
01/2021 - 01/2018
3Cognitive Dysfunction
02/2019 - 12/2014
3Lymphatic Metastasis
05/2018 - 07/2007
3Insulin Resistance
01/2015 - 01/2007
3Esophageal Neoplasms (Esophageal Cancer)
04/2012 - 09/2008

Drug/Important Bio-Agent (IBA)

21G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2021 - 10/2004
21Proteins (Proteins, Gene)FDA Link
01/2021 - 11/2002
17Protons (Proton)IBA
01/2021 - 10/2004
13Biomarkers (Surrogate Marker)IBA
11/2021 - 11/2008
10CytokinesIBA
11/2021 - 12/2003
10AntithrombinsIBA
12/2020 - 09/2016
9Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
02/2021 - 01/2013
9lysophosphatidic acidIBA
01/2019 - 02/2004
8DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2003
8Pharmaceutical PreparationsIBA
10/2019 - 05/2008
7Messenger RNA (mRNA)IBA
01/2022 - 03/2003
7Acetylcholine (Acetylcholine Chloride)FDA Link
10/2021 - 05/2005
7EnzymesIBA
12/2020 - 09/2010
7Dacarbazine (DIC)FDA LinkGeneric
07/2020 - 12/2015
6Angiotensin Receptor AntagonistsIBA
01/2022 - 04/2007
6C-Reactive ProteinIBA
01/2019 - 09/2003
5Calcium Channel Blockers (Blockers, Calcium Channel)IBA
01/2022 - 01/2010
5NivolumabIBA
11/2021 - 01/2018
4Therapeutic UsesIBA
01/2021 - 03/2007
4MetalsIBA
01/2021 - 07/2008
4Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
12/2020 - 11/2015
4Donepezil (Aricept)FDA LinkGeneric
02/2019 - 03/2003
4AcetylcholinesteraseIBA
01/2018 - 12/2005
4Small Interfering RNA (siRNA)IBA
11/2017 - 02/2004
4LipopolysaccharidesIBA
12/2015 - 03/2007
4Docetaxel (Taxotere)FDA Link
02/2012 - 04/2010
4Polymyxin B (Aerosporin)FDA LinkGeneric
06/2011 - 03/2007
4LipidsIBA
09/2010 - 02/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2022 - 12/2009
3Interleukin-6 (Interleukin 6)IBA
08/2021 - 01/2019
3RNA (Ribonucleic Acid)IBA
06/2021 - 06/2019
3Oxaliplatin (Eloxatin)FDA LinkGeneric
04/2021 - 04/2018
3Prednisolone (Predate)FDA LinkGeneric
01/2021 - 01/2020
3Type C PhospholipasesIBA
11/2020 - 03/2003
3Norepinephrine (Noradrenaline)FDA LinkGeneric
08/2020 - 08/2002
3ParaffinIBA
03/2020 - 06/2013
3Formaldehyde (Formol)FDA Link
03/2020 - 06/2013
3Histones (Histone)IBA
01/2019 - 12/2015
3Irinotecan (Camptosar)FDA LinkGeneric
04/2018 - 01/2016
3Cholinergic Agents (Cholinergics)IBA
01/2018 - 06/2008
3Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2017 - 02/2008
3Triglycerides (Triacylglycerol)IBA
01/2015 - 01/2007
3HDL CholesterolIBA
01/2015 - 01/2007
3Lysophosphatidic Acid ReceptorsIBA
06/2012 - 02/2004

Therapy/Procedure

33Therapeutics
02/2021 - 12/2006
8Drug Therapy (Chemotherapy)
11/2021 - 01/2004
7Gastrectomy
11/2021 - 07/2007
6Percutaneous Coronary Intervention
10/2021 - 05/2005
5Aftercare (After-Treatment)
12/2014 - 01/2009
4Adjuvant Chemotherapy
04/2021 - 01/2015
4Hemoperfusion
06/2011 - 03/2007
3Blood Transfusion (Blood Transfusions)
03/2020 - 02/2006
3Radiotherapy
02/2020 - 02/2005
3Stents
12/2019 - 02/2012
3Gastrostomy
01/2019 - 12/2014
3Pancreatectomy
01/2017 - 11/2009